Interface dermatitis is a classic histologic pattern that reflects injury at the junction between the epidermis and dermis, also known as the dermoepidermal junction. This region is critical for skin integrity, and when it becomes a target of immune-mediated damage,…
Autoimmune diseases occur when the immune system mistakenly targets the body’s own tissues, leading to chronic inflammation and organ damage. While these conditions are common, diagnosing them is often far from straightforward. Symptoms can overlap, laboratory findings may be nonspecific,…
Lymphocytic infiltration is a frequently reported histologic finding that reflects the movement of immune cells into tissues. These lymphocytes, which are central to the body’s immune defense, often appear in response to inflammation, infection, autoimmune conditions, or cancer. While the…
